Select Publications
NOV 2020
CRISPR based editing of SIV proviral DNA in ART treated non-human primates
Mancuso P, Chen C, Kaminski R, Gordon J, Liao S, Robinson JA, Smith MD, Liu H, Sariyer IK, Sariyer R, Peterson TA, Donadoni M, Williams JB, Siddiqui S, Bunnell BA, Ling B, MacLean AG, Burdo TH, Khalili K.
AUG 2020
A scoutRNA Is Required for Some Type V CRISPR-Cas Systems
Harrington LB, Ma E, Chen JS, Witte IP, Gertz D, Paez-Espino D, Al-Shayeb B, Kyrpides NC, Burstein D, Banfield JF, Doudna JA.
JUL 2019
Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice
Dash, P. K., Kaminski, R., Bella, R., Su, H., Mathews, S., Ahooyi, T. M., Chen, C., Mancuso, P., Sariyer, R., Ferrante, P., Donadoni, M., Robinson, J. A., Sillman, B., Lin, Z., Hilaire, J. R., Banoub, M., Elango, M., Gautam, N., Mosley, R. L., Poluektova, L. Y., … Gendelman, H. E.
MAR 2019
Magnetically guided non-invasive CRISPR-Cas9/gRNA delivery across blood-brain barrier to eradicate latent HIV-1 infection
Kaushik, A., Yndart, A., Atluri, V., Tiwari, S., Tomitaka, A., Gupta, P., Jayant, R. D., Alvarez-Carbonell, D., Khalili, K., & Nair, M.
DEC 2018
Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection
Allen Alexander G., Chung Cheng-Han, Atkins Andrew, Dampier Will, Khalili Kamel, Nonnemacher Michael R., Wigdahl Brian
DEC 2018
Toward the Cure of HIV-1 Infection: Lessons Learned and Yet to be Learned as New Strategies are Developed
Jacobson JM, Khalili K.
NOV 2018
Broad-Spectrum and Personalized Guide RNAs for CRISPR/Cas9 HIV-1 Therapeutics
Dampier W, Sullivan NT, Mell JC, Pirrone V, Ehrlich GD, Chung CH, Allen AG, DeSimone M, Zhong W, Kercher K, Passic S, Williams JW, Szep Z, Khalili K, Jacobson JM, Nonnemacher MR, Wigdahl B.
JUN 2018
Removal of HIV DNA by CRISPR from Patient Blood Engrafts in Humanized Mice
Bella, R., Kaminski, R., Mancuso, P., Young, W. B., Chen, C., Sariyer, R., Fischer, T., Amini, S., Ferrante, P., Jacobson, J. M., Kashanchi, F., & Khalili, K.
APR 2018
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
Chen JS, Ma E, Harrington LB, Da Costa M, Tian X, Palefsky JM, Doudna JA.
NOV 2017
CRISPR Editing Technology in Biological and Biomedical Investigation
White MK, Kaminski R, Young WB, Roehm PC, Khalili K.
MAY 2017
In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models
Yin C, Zhang T, Qu X, Zhang Y, Putatunda R, Xiao X, Li F, Xiao W, Zhao H, Dai S, Qin X, Mo X, Young WB, Khalili K, Hu W.
DEC 2016
Gene Editing Approaches against Viral Infections and Strategy to Prevent Occurrence of Viral Escape
White MK, Hu W, Khalili K.
AUG 2016
Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study
Kaminski R, Bella R, Yin C, Otte J, Ferrante P, Gendelman HE, Li H, Booze R, Gordon J, Hu W, Khalili K.
AUG 2016
Negative Feedback Regulation of HIV-1 by Gene Editing Strategy
Kaminski, R., Chen, Y., Salkind, J., Bella, R., Young, W. B., Ferrante, P., Karn, J., Malcolm, T., Hu, W., & Khalili, K.
APR 2016
Inhibition of HSV-1 Replication by Gene Editing Strategy
Roehm, P. C., Shekarabi, M., Wollebo, H. S., Bellizzi, A., He, L., Salkind, J., & Khalili, K.
MAR 2016
Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing
Kaminski, R., Chen, Y., Fischer, T., Tedaldi, E., Napoli, A., Zhang, Y., Karn, J., Hu, W., & Khalili, K.
DEC 2015
Animal Models for Progressive Multifocal Leukoencephalopathy
White MK, Gordon J, Berger JR, Khalili K.
SEP 2015
CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection
Wollebo HS, Bellizzi A, Kaminski R, Hu W, White MK, Khalili K.
JUN 2015
Genome editing strategies: potential tools for eradicating HIV-1/AIDS
Khalili K, Kaminski R, Gordon J, Cosentino L, Hu W.
AUG 2014
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
Hu W, Kaminski R, Yang F, Zhang Y, Cosentino L, Li F, Luo B, Alvarez-Carbonell D, Garcia-Mesa Y, Karn J, Mo X, Khalili K.