Technology

A novel approach to CRISPR

EXCISION

Approach

Dual gRNAs excise large sections of viral DNA, eliminating viral escape and reproduction. The result is curative.

Large Deletion,

No Probability of Escape

DISCOVERY

Platform

Excision's platform enables in silico design of probes to analyze on- and off-target effects and integrates computational methods to design the most effective guide RNAs.

We are transforming drug discovery and target validation from traditional to digital.

THERAPEUTIC

Pipeline

Discovery/Validation

IND-Enabling

Cleared IND

Clinical Trials

EBT-101 HIV AAV9 Cas9 dual gRNA Therapeutic

EBT-103 PML/JCV AAV9 Cas9 dual gRNA T-antigen Therapeutic

EBT-104 HSV AAV or non-viral Cas9 dual gRNA Therapeutic

EBT-107 HBV AAV or non-viral CasX dual gRNA Therapeutic